Novel nanofiber-based scaffold for rotator cuff repair and augmentation.

@article{Moffat2009NovelNS,
  title={Novel nanofiber-based scaffold for rotator cuff repair and augmentation.},
  author={Kristen L. Moffat and Anne S-P Kwei and Jeffrey P. Spalazzi and Stephen B. Doty and William N. Levine and H. H. Lu},
  journal={Tissue engineering. Part A},
  year={2009},
  volume={15 1},
  pages={115-26}
}
The debilitating effects of rotator cuff tears and the high incidence of failure associated with current grafts underscore the clinical demand for functional solutions for tendon repair and augmentation. To address this challenge, we have designed a poly(lactide-co-glycolide) (PLGA) nanofiber-based scaffold for rotator cuff tendon tissue engineering. In addition to scaffold design and characterization, the objective of this study was to evaluate the attachment, alignment, gene expression, and… CONTINUE READING
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