Novel mutations in the V2 vasopressin receptor gene in two pedigrees with congenital nephrogenic diabetes insipidus.

@article{Yuasa1994NovelMI,
  title={Novel mutations in the V2 vasopressin receptor gene in two pedigrees with congenital nephrogenic diabetes insipidus.},
  author={Hisako Yuasa and Masafumi Ito and Yutaka Oiso and Manabu Kurokawa and Tomoyuki Watanabe and Yasuo Oda and Tatsuya Ishizuka and Naoki Tani and Shosuke Ito and Atsuko Shibata},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1994},
  volume={79 2},
  pages={
          361-5
        }
}
Novel mutations in the V2 vasopressin receptor gene were identified in two Japanese pedigrees with X-linked congenital nephrogenic diabetes insipidus. The V2 receptor belongs to the family of G-protein-coupled receptors that contain seven distinct transmembrane domains, and the V2 receptor gene is encoded by three exons. The coding regions amplified by polymerase chain reaction were directly sequenced. In a pedigree, one of four consecutive guanine sequences (nucleotides 528-531) in the second… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Similar Papers

Loading similar papers…