Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer

@article{Yassaee2001NovelMI,
  title={Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer},
  author={Vahid R Yassaee and S Zeinali and Iraj Harirchi and Soghra Jarvandi and Mohammad Ali Mohagheghi and David P Hornby and Ann E Dalton},
  journal={Breast Cancer Research : BCR},
  year={2001},
  volume={4},
  pages={R6 - R6}
}
Breast cancer is the most common female malignancy and a major cause of death in middle-aged women. So far, germline mutations in the BRCA1 and BRCA2 genes in patients with early-onset breast and/or ovarian cancer have not been identified within the Iranian population. With the collaboration of two main centres for cancer in Iran, we obtained clinical information, family history and peripheral blood from 83 women under the age of 45 with early-onset breast cancer for scanning of germline… CONTINUE READING