Novel mutations found in mitochondrial diabetes in Chinese Han population.

@article{Liu2007NovelMF,
  title={Novel mutations found in mitochondrial diabetes in Chinese Han population.},
  author={Songmei Liu and Xin Zhou and Fang Zheng and Xia Li and Fang Liu and Hong-mei Zhang and Yan Xie},
  journal={Diabetes research and clinical practice},
  year={2007},
  volume={76 3},
  pages={
          425-35
        }
}
Mitochondria provide cells with most of the energy in the form of ATP. Mutations in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM) because ATP plays a critical role in the production and the release of insulin. To systematically determine mutant loci and to investigate their association with T2DM in Chinese Han population, 17 commonly reported mutant loci were screened in 236 cases of T2DM and 240 normal controls by PCR-RFLP, allele-specific PCR (AS-PCR) and DNA… CONTINUE READING

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