Novel mutation processes in the evolution of a haploid minisatellite, MSY1: array homogenization without homogenization.

@article{Bouzekri1998NovelMP,
  title={Novel mutation processes in the evolution of a haploid minisatellite, MSY1: array homogenization without homogenization.},
  author={Nourdine Bouzekri and Philip Graham Taylor and Michael F. Hammer and Mark A Jobling},
  journal={Human molecular genetics},
  year={1998},
  volume={7 4},
  pages={655-9}
}
The Y-specific locus MSY1 is the only known haploid minisatellite, and displays an extremely high degree of structural diversity which can be assayed by minisatellite variant repeat PCR (MVR-PCR). One group of alleles, in an African-specific class of Y chromosomes (haplogroup 8), behaves unusually in the conventional MVR-PCR assay, and sequencing demonstrates that this is because repeat units in these alleles contain an additional base substitution. We have designed a new MVR-PCR system to… CONTINUE READING

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