Novel morphology change of Au-Methotrexate conjugates: From nanochains to discrete nanoparticles.

Abstract

A novel morphology change of Au-methotrexate (Au-MTX) conjugates that could transform from nanochains to discrete nanoparticles was achieved by a simple, one-pot, and hydrothermal growth method. Herein, MTX was used efficiently as a complex-forming agent, reducing agent, capping agent, and importantly a targeting anticancer drug. The formation mechanism… (More)
DOI: 10.1016/j.ijpharm.2016.10.022

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@article{Wang2016NovelMC, title={Novel morphology change of Au-Methotrexate conjugates: From nanochains to discrete nanoparticles.}, author={Wei-Yuan Wang and Xiu-fen Zhao and Xiao-Han Ju and Yu Wang and Lin Wang and Shu-Ping Li and Xiao-Dong Li}, journal={International journal of pharmaceutics}, year={2016}, volume={515 1-2}, pages={221-232} }