Novel mitochondrial extensions provide evidence for a link between microtubule-directed movement and mitochondrial fission.

@article{Bowes2008NovelME,
  title={Novel mitochondrial extensions provide evidence for a link between microtubule-directed movement and mitochondrial fission.},
  author={Timothy J Bowes and Radhey S Gupta},
  journal={Biochemical and biophysical research communications},
  year={2008},
  volume={376 1},
  pages={40-5}
}
Mitochondrial dynamics play an important role in a large number of cellular processes. Previously, we reported that treatment of mammalian cells with the cysteine-alkylators, N-ethylmaleimide and ethacrynic acid, induced rapid mitochondrial fusion forming a large reticulum approximately 30 min after treatment. Here, we further investigated this phenomenon using a number of techniques including live-cell confocal microscopy. In live cells, drug-induced fusion coincided with a cessation of fast… CONTINUE READING