Novel method of tetramic acid synthesis: silver-catalyzed carbon dioxide incorporation into propargylic amine and intramolecular rearrangement.

Abstract

Tetramic acid derivatives have been studied as biologically active heterocycle structures for pharmaceutical or agricultural chemicals. Conventional preparative approaches often require highly functionalized starting materials and harsh heating conditions in basic media. The present report provides a conceptually new synthetic strategy for the synthesis of… (More)
DOI: 10.1021/ol500806u

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@article{Ishida2014NovelMO, title={Novel method of tetramic acid synthesis: silver-catalyzed carbon dioxide incorporation into propargylic amine and intramolecular rearrangement.}, author={Tomonobu Ishida and Ryo Kobayashi and Tohru Yamada}, journal={Organic letters}, year={2014}, volume={16 9}, pages={2430-3} }