Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation.

@article{Yanaka2003NovelMP,
  title={Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation.},
  author={Noriyuki Yanaka and Yuji Imai and Eri Kawai and Hiroyuki Akatsuka and Koji Wakimoto and Yoshihito Nogusa and Norihisa Kato and Hiroaki Chiba and Eriko Kotani and Kenji Omori and Naoki Sakurai},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 44},
  pages={43595-602}
}
Osteoblast maturation is a multistep series of events characterized by an integrated cascade of gene expression that are accompanied by specific phenotypic alterations. To find new osteoblast-related genes we cloned differentially expressed cDNAs characteristic of specific differentiation stages in the mouse osteoblast-like MC3T3-E1 cells by a differential display method. We identified a novel cDNA encoding a putative glycerophosphodiester phosphodiesterase, GDE3, which specifically was… CONTINUE READING
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