Novel mechanisms of sympathetic regulation in chronic heart failure.

  title={Novel mechanisms of sympathetic regulation in chronic heart failure.},
  author={Irving H. Zucker},
  volume={48 6},
The idea that activation of the sympathetic nervous system is part and parcel of the apparent positive feedback cycle of cardiac deterioration in the setting of chronic heart failure (CHF) is not a new one. Several reviews have clearly summarized the evidence for this concept using both clinical data and information from experimental models.1–4 Evidence from both neural recordings and measurement of circulating catecholamines clearly document a central origin for much of the sympathetic… CONTINUE READING
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