Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014

@inproceedings{Roer2017NovelMV,
  title={Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014},
  author={Louise Roer and Frank Hansen and Marc Stegger and Ute Wolff S{\"o}nksen and Henrik Hasman and Anette Marie Hammerum},
  booktitle={Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin},
  year={2017}
}
A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria. 

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