Novel management of oral cancer: a paradigm of predictive oncology.

  title={Novel management of oral cancer: a paradigm of predictive oncology.},
  author={Jon Sudb\o},
  journal={Clinical medicine & research},
  volume={2 4},
  • Jon Sudbø
  • Published 2004 in Clinical medicine & research
The rationale for molecular-targeted prevention of oral cancer is strong. Oral cancer is a major global threat to public health with 300,000 new cases diagnosed worldwide on an annual basis. Notably, the great morbidity and mortality rates of this devastating disease have not improved in decades. Oral cancer development is a tobacco-related multistep and multifocal process involving field carcinogenesis and intraepithelial clonal spread. Biomarkers of genomic instability, such as aneuploidy and… CONTINUE READING
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