Novel macrolactins as antibiotic lactones from a marine bacterium.

@article{Nagao2001NovelMA,
  title={Novel macrolactins as antibiotic lactones from a marine bacterium.},
  author={Tomokazu Nagao and Kyoko Adachi and Miho Sakai and Miyuki Nishijima and Hiroko Sano},
  journal={The Journal of antibiotics},
  year={2001},
  volume={54 4},
  pages={333-9}
}
Seven new macrolactins (named G~M) and known macrolactins A and F were isolated from a culture broth of Bacillus sp. PP19-H3. The strain had been isolated from the macroalga, Schizymenia dubyi. Macrolactin A, which was 24-membered lactone, had previously been reported to show antibacterial, cytotoxic and antiviral activities. The new macrolactins include 22-membered ring or dicyclic lactone in addition to geometric isomers of known macrolactins A and F. The antibacterial activities of all the… CONTINUE READING

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