Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells.

@article{Leung2013NovelLN,
  title={Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells.},
  author={Amy AM Leung and Candi Trac and Wen Jun Jin and Linda L. Lanting and Asad Akbany and P{\aa}l S{\ae}trom and Dustin E. Schones and Rama Natarajan},
  journal={Circulation research},
  year={2013},
  volume={113 3},
  pages={266-78}
}
RATIONALE Misregulation of angiotensin II (Ang II) actions can lead to atherosclerosis and hypertension. Evaluating transcriptomic responses to Ang II in vascular smooth muscle cells (VSMCs) is important to understand the gene networks regulated by Ang II, which might uncover previously unidentified mechanisms and new therapeutic targets. OBJECTIVE To identify all transcripts, including novel protein-coding and long noncoding RNAs, differentially expressed in response to Ang II in rat VSMCs… CONTINUE READING
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