Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope.

@article{Shao2015NovelLO,
  title={Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope.},
  author={Xiaowei Shao and Keiko Kawauchi and G. V. Shivashankar and Alexander D Bershadsky},
  journal={Biology open},
  year={2015},
  volume={4 11},
  pages={1569-75}
}
The formin family proteins are important regulators of actin polymerization that are involved in many cellular processes. However, little is known about their specific cellular localizations. Here, we show that Diaphanous-related formin-3 (mDia2) localizes to the cytoplasmic side of the nuclear envelope. This localization of mDia2 to the nuclear rim… CONTINUE READING