Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.

@article{Ries2013NovelKM,
  title={Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.},
  author={Marco I. Ries and Hazrat Ali and Peter P Lankhorst and Thomas Hankemeier and Roel A. L. Bovenberg and Arnold J M Driessen and Rob J. Vreeken},
  journal={The Journal of biological chemistry},
  year={2013},
  volume={288 52},
  pages={37289-95}
}
Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various previously ascribed synthetase genes of the roquefortine/meleagrin pathway to their corresponding products. Next to the structural characterization of… CONTINUE READING