Novel intercellular communication system in Escherichia coli that confers antibiotic resistance between physically separated populations.

@article{Heal2002NovelIC,
  title={Novel intercellular communication system in Escherichia coli that confers antibiotic resistance between physically separated populations.},
  author={R D Heal and Andrew T. Parsons},
  journal={Journal of applied microbiology},
  year={2002},
  volume={92 6},
  pages={1116-22}
}
AIMS To determine whether intercellular signalling can occur between physically separated populations of Escherichia coli. METHODS AND RESULTS Intercellular signalling between physically discrete populations of E. coli BL21 was analysed in bi-partite Petri dishes. Transfer of a growth-promoting signal resulted in induction of resistance to the antibiotic ampicillin. Optimal expression of the signal occurred when the signalling population was established as a bacterial lawn for 24 h. This… CONTINUE READING