Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis.

@article{Harth1996NovelII,
  title={Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis.},
  author={Guenter Harth and Bo Yon Lee and Jian Wang and Daniel L. Clemens and Marcus A. Horwitz},
  journal={Infection and immunity},
  year={1996},
  volume={64 8},
  pages={3038-47}
}
The 30/32-kDa complex of major secretory proteins are among the most important and intensively studied proteins of Mycobacterium tuberculosis. The proteins have been demonstrated to be immunoprotective and to play a central role in the physiology of the mycobacterium. In this study, we present a series of novel insights into this key protein complex arising out of a combination of genetic, biochemical, and immunocytochemical analyses. Our genetic analyses (i) indicate that the genes are… CONTINUE READING

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