Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis.

@article{Chang2012NovelII,
  title={Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis.},
  author={Fan-Chi Chang and Yu-Hsiang Chou and Yi-Ting Chen and Shuei-Liong Lin},
  journal={Journal of the Formosan Medical Association = Taiwan yi zhi},
  year={2012},
  volume={111 11},
  pages={589-98}
}
Renal fibrosis is a disease affecting millions worldwide and is a harbinger of progressive renal failure. Understanding the mechanisms of renal fibrosis is important for discovering new therapies that are required to prevent loss of renal function. Recently, we identified pericytes that line the kidney microvasculature as the precursor cells of the scar-producing myofibroblasts during kidney injury. Kidney pericytes are extensively branched cells embedded within the capillary basement membrane… CONTINUE READING
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Macrophages in kidney injury and repair

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