Novel insights in the regulation and mechanism of androgen action on bone

@article{Sinnesael2013NovelII,
  title={Novel insights in the regulation and mechanism of androgen action on bone},
  author={M. Sinnesael and F. Claessens and S. Boonen and D. Vanderschueren},
  journal={Current Opinion in Endocrinology & Diabetes and Obesity},
  year={2013},
  volume={20},
  pages={240–244}
}
  • M. Sinnesael, F. Claessens, +1 author D. Vanderschueren
  • Published 2013
  • Medicine
  • Current Opinion in Endocrinology & Diabetes and Obesity
  • Purpose of reviewThis review provides an update on the associations of testosterone, estrogens, sex hormone binding globulin, GH-IGF-I, osteocalcin and mechanical loading with relevance to skeletal health. Recent findingsThe simple concept of a dual model of action of androgens, i.e. either directly via the androgen receptor or indirectly by estrogens, is proving more complicated because of novel interactions of these hormones and their receptors with other hormonal as well as mechanical… CONTINUE READING
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