Novel indole S,O-bisdesmoside, calanthoside, the precursor glycoside of tryptanthrin, indirubin, and isatin, with increasing skin blood flow promoting effects, from two Calanthe species (Orchidaceae).

@article{Yoshikawa1998NovelIS,
  title={Novel indole S,O-bisdesmoside, calanthoside, the precursor glycoside of tryptanthrin, indirubin, and isatin, with increasing skin blood flow promoting effects, from two Calanthe species (Orchidaceae).},
  author={Masayuki Yoshikawa and Toshiyuki Murakami and Akinobu Kishi and Tetsuo Sakurama and Hisashi Matsuda and Manabu Nomura and Michinori Kubo},
  journal={Chemical \& pharmaceutical bulletin},
  year={1998},
  volume={46 5},
  pages={
          886-8
        }
}
The methanolic extracts from Calanthe discolor LINDL. and C. liukiuensis SCHLTR. were found to exhibit hair restoring and skin blood flow promoting activities. Through bioassay-guided separation using the skin blood flow increasing effect, a novel indole S,O-bisdesmoside, calanthoside, was isolated together with three new components, glucoindican, calaliukiuenoside, and calaphenanthrenol, and known compounds such as tryptanthrin, indirubin, isatin, and indican. The structures of the new… Expand
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