Novel immunotherapies for psoriasis.

  title={Novel immunotherapies for psoriasis.},
  author={Khusru Asadullah and H P Volk and Wolfram Sterry},
  journal={Trends in immunology},
  volume={23 1},
New insights into the pathophysiology of psoriasis have suggested possibilities for targeted therapeutic intervention. Several novel, systemic immunomodulatory therapies are currently in clinical development and results of recent clinical trials are remarkable. These include approaches targeting antigen presentation and costimulation, T-cell activation and leukocyte adhesion, the action of proinflammatory mediators and the administration of anti-inflammatory cytokines. These trials contribute… CONTINUE READING


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