Novel human serum protein from fibroblast plasma membrane

@article{Ruoslahti1974NovelHS,
  title={Novel human serum protein from fibroblast plasma membrane},
  author={Erkki Ruoslahti and Antti Vaheri},
  journal={Nature},
  year={1974},
  volume={248},
  pages={789-791}
}
CELL surface components play a major role in the control of normal cell interactions and in the altered growth control and antigenic properties of malignant cells1. To characterise tissue-specific cell surface proteins we undertook an immunochemical study of the material released from cells by mild proteolytic treatment. Our studies have disclosed a fibroblast-specific cell surface and serum antigen in chicken2. The amount of this antigen is greatly reduced in chicken fibroblasts transformed by… CONTINUE READING

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