Novel histologic scoring system for long-term allograft fibrosis after liver transplantation in children.

@article{Venturi2012NovelHS,
  title={Novel histologic scoring system for long-term allograft fibrosis after liver transplantation in children.},
  author={Carla Venturi and Christine Sempoux and Javier Bueno and Joan Carles Ferreres Pi{\~n}as and Christophe Bourdeaux and Jorge Abarca-Quinones and Jacques Rahier and Raymond Reding},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 11},
  pages={2986-96}
}
The existing systems for scoring fibrosis were not developed to evaluate transplanted livers. Our aim was to design and validate a novel fibrosis scoring system specifically adapted to assess liver allograft fibrosis (LAF). Clinical data, histology, transient elastography (TE) and AST/platelet ratio index (APRI) were reviewed in 38 pediatric liver transplant (LT) recipients. Protocol liver biopsies performed at 6 months and 7 years post-LT were reviewed by three pathologists who assessed LAF… CONTINUE READING
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