Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice

@article{Vigolo2015NovelHD,
  title={Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice},
  author={A. Vigolo and A. Ossato and C. Trapella and F. Vincenzi and M. Marti},
  journal={Neuropharmacology},
  year={2015},
  volume={95},
  pages={68-82}
}
JWH-018 is a synthetic CB1 and CB2 agonist illegally marketed as products named "Spice" or "herbal blend" for its psychoactive effects which are much higher than those produced by cannabis. In the last year, the European Monitoring Centre for Drugs and Drug Addiction reported to the Italian National Early Warning System the seizure of plant material containing new halogenated derivatives of JWH-018 (JWH-018 Cl and JWH-018 Br). The present study aimed to investigate the in vitro and in vivo… Expand
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