Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin.

@article{Andersen2009NovelGM,
  title={Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Gu{\'e}rin.},
  author={Claire A. Swetman Andersen and Ida Rosenkrands and Anja Weinreich Olsen and Pernille Nordly and Dennis E. Christensen and Roland Lang and Carsten J Kirschning and J{\'e}ssica Marcela de Luna Gomes and Veemal Bhowruth and David E. Minnikin and Gurdyal S Besra and Frank Follmann and Peter Hvilsh\oj Andersen and Else Marie Agger},
  journal={Journal of immunology},
  year={2009},
  volume={183 4},
  pages={2294-302}
}
The immunostimulatory activity of lipids associated with the mycobacterial cell wall has been recognized for several decades and exploited in a large variety of different adjuvant preparations. Previously, we have shown that a mycobacterial lipid extract from Mycobacterium bovis bacillus Calmette-Guérin delivered in cationic liposomes was a particular efficient Th1-inducing adjuvant formulation effective against tuberculosis. Herein, we have dissected the adjuvant activity of the bacillus… CONTINUE READING
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