Novel functional variants at the GWAS-implicated loci might confer risk to major depressive disorder, bipolar affective disorder and schizophrenia

@inproceedings{Bryzgalov2018NovelFV,
  title={Novel functional variants at the GWAS-implicated loci might confer risk to major depressive disorder, bipolar affective disorder and schizophrenia},
  author={Leonid O. Bryzgalov and Elena E Korbolina and Ilja I. Brusentsov and Elena Yu Leberfarb and Natalia P. Bondar and Tatiana I. Merkulova},
  booktitle={BMC Neuroscience},
  year={2018}
}
BackgroundA challenge of understanding the mechanisms underlying cognition including neurodevelopmental and neuropsychiatric disorders is mainly given by the potential severity of cognitive disorders for the quality of life and their prevalence. However, the field has been focused predominantly on protein coding variation until recently. Given the importance of tightly controlled gene expression for normal brain function, the goal of the study was to assess the functional variation including… CONTINUE READING
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