Novel formaldehyde-activating enzyme in Methylobacterium extorquens AM1 required for growth on methanol.

Abstract

Formaldehyde is toxic for all organisms from bacteria to humans due to its reactivity with biological macromolecules. Organisms that grow aerobically on single-carbon compounds such as methanol and methane face a special challenge in this regard because formaldehyde is a central metabolic intermediate during methylotrophic growth. In the alpha… (More)

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