Novel epigenetic determinants of type 2 diabetes in Mexican-American families.

  title={Novel epigenetic determinants of type 2 diabetes in Mexican-American families.},
  author={Hemant Kulkarni and Mark Z Kos and Jennifer L. Neary and Thomas D. Dyer and Jack W. Kent and Harald H. H. G{\"o}ring and S. A. Cole and Anthony Gean Comuzzie and Laura Almasy and Michael C. Mahaney and Joanne E. Curran and John Blangero and Melanie A. Carless},
  journal={Human molecular genetics},
  volume={24 18},
Although DNA methylation is now recognized as an important mediator of complex diseases, the extent to which the genetic basis of such diseases is accounted for by DNA methylation is unknown. In the setting of large, extended families representing a minority, high-risk population of the USA, we aimed to characterize the role of epigenome-wide DNA methylation in type 2 diabetes (T2D). Using Illumina HumanMethylation450 BeadChip arrays, we tested for association of DNA methylation at 446 356… CONTINUE READING
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SNPlocs.Hsapiens.dbSNP.20120608: SNP locations for Homo sapiens (dbSNP Build 137). R package version 0.99.9

  • H. Pages
  • Human Molecular Genetics,
  • 2015
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