Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.

Abstract

The tender leaves of Rubus corchorifolius L. f. have been consumed as tea for drinking in China since ancient times. In this study, a novel ent-kaurane diterpenoid was isolated and identified from R. corchorifolius L. f. leaves as ent-kaur-2-one-16β,17-dihydroxy-acetone-ketal (DEK). DEK suppressed the growth of HCT116 human colon cancer cells with an IC50… (More)
DOI: 10.1021/acs.jafc.6b05376

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@article{Chen2017NovelED, title={Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.}, author={Xuexiang Chen and Xian Wu and Wen Ouyang and Min Gu and Zili Gao and Mingyue Song and Yunjiao Chen and Yanyin Lin and Yong Cao and Hang Xiao}, journal={Journal of agricultural and food chemistry}, year={2017}, volume={65 8}, pages={1566-1573} }