Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation

@inproceedings{Raboune2014NovelEN,
  title={Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation},
  author={Siham Raboune and Jordyn M. Stuart and Emma Leishman and Sara M. Takacs and Brandon P. Rhodes and Arjun Basnet and Evan Jameyfield and Douglas McHugh and Theodore S. Widlanski and Heather B. Bradshaw},
  booktitle={Front. Cell. Neurosci.},
  year={2014}
}
A family of endogenous lipids, structurally analogous to the endogenous cannabinoid, N-arachidonoyl ethanolamine (Anandamide), and called N-acyl amides have emerged as a family of biologically active compounds at TRP receptors. N-acyl amides are constructed from an acyl group and an amine via an amide bond. This same structure can be modified by changing either the fatty acid or the amide to form potentially hundreds of lipids. More than 70 N-acyl amides have been identified in nature. We have… CONTINUE READING

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Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation

  • S Citation Raboune, JM Stuart, +7 authors HB Bradshaw
  • doi: 10.3389/fncel
  • 2014

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY)

  • Raboune, Stuart, +7 authors Bradshaw
  • 2014

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