Novel dimeric β-helical model of an ice nucleation protein with bridged active sites

@inproceedings{Garnham2011NovelD,
  title={Novel dimeric β-helical model of an ice nucleation protein with bridged active sites},
  author={Christopher P. Garnham and Robert L. Campbell and Virginia K. Walker and Peter L Davies},
  booktitle={BMC Structural Biology},
  year={2011}
}
Ice nucleation proteins (INPs) allow water to freeze at high subzero temperatures. Due to their large size (>120 kDa), membrane association, and tendency to aggregate, an experimentally-determined tertiary structure of an INP has yet to be reported. How they function at the molecular level therefore remains unknown. Here we have predicted a novel β-helical fold for the INP produced by the bacterium Pseudomonas borealis. The protein uses internal serine and glutamine ladders for stabilization… CONTINUE READING

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References

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Showing 1-10 of 41 references

The PyMOL Molecular Graphics System

WL DeLano
DeLano Scientific, San Carlos, • 2002
View 5 Excerpts
Highly Influenced

A model of the three-dimensional structure of ice nucleation proteins.

Journal of molecular biology • 1993
View 5 Excerpts
Highly Influenced

Coot: model-building tools for molecular graphics.

Acta crystallographica. Section D, Biological crystallography • 2004
View 3 Excerpts
Highly Influenced

A phased translation function

RJ Read, AJ Schierbeek
Journal of Applied Crystallography • 1988
View 3 Excerpts
Highly Influenced

Anchored clathrate waters bind antifreeze proteins to ice.

Proceedings of the National Academy of Sciences of the United States of America • 2011
View 5 Excerpts

Overview of the CCP4 suite and current developments

Acta crystallographica. Section D, Biological crystallography • 2011
View 1 Excerpt

Minimalist design of water-soluble cross-beta architecture.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 1 Excerpt

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