Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening.

@article{Ramesh2011NovelDA,
  title={Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening.},
  author={Balasubramaniyan Ramesh and Chetan M. Bhalgat},
  journal={European journal of medicinal chemistry},
  year={2011},
  volume={46 5},
  pages={1882-91}
}
In the present study, we have synthesized novel dihydropyrimidines (1a-j), their dimethylated adducts (2a-j), and hydrazine derivatives (3a-j) of 2a-j and subsequently their pyrazole derivatives (4a-j). Elemental analysis, IR, 1H NMR and mass spectral data elucidated structure of newly synthesized compounds. Some of these novel derivatives showed moderate… CONTINUE READING