Novel digitalis-like factor, marinobufotoxin, isolated from cultured Y-1 cells, and its hypertensive effect in rats.

Abstract

Marinobufagenin and telecinobufagin have been identified as digitalis-like factors in mammals. In toads, marinobufagenin-related compounds, such as marinobufotoxin (MBT), have been isolated in some tissues but not in mammals, and its biological action has not been elucidated. Herein, we aimed to explore the possible production and/or secretion of MBT and… (More)

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Cite this paper

@article{Yoshika2007NovelDF, title={Novel digitalis-like factor, marinobufotoxin, isolated from cultured Y-1 cells, and its hypertensive effect in rats.}, author={Masamichi Yoshika and Yutaka Komiyama and Motomi Konishi and Toshifumi Akizawa and Takahisa Kobayashi and Mutsuhiro Date and Shinzo Kobatake and M Masuda and Hiroya Masaki and Hakuo Takahashi}, journal={Hypertension}, year={2007}, volume={49 1}, pages={209-14} }