Novel derivatives of monascus pigment having a high CETP inhibitory activity.

Abstract

The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compounds were synthesised by incorporating 19… (More)
DOI: 10.1080/14786419.2014.905561

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