Novel cytotoxic principles of Formosan Ganoderma lucidum.

  title={Novel cytotoxic principles of Formosan Ganoderma lucidum.},
  author={C. N. Lin and W P Tome and S. J. Won},
  journal={Journal of natural products},
  volume={54 4},
Two new steryl esters, ergosta-7,22-dien-3 beta-yl linoleate [1] and 5 alpha,8 alpha-epidioxyergosta-6,22-dien-3 beta-yl linoleate [3], and a novel steroid, ergosta-7,22-diene- 3 beta,3 alpha,9 alpha-triol [5], have been isolated from the fruiting bodies of Formosan Ganoderma lucidum and characterized. A new lanostanoid, 3 beta-hydroxy-26-oxo-5 alpha-lanosta- 8,24-dien-11-one, and the new steroid exhibited potent inhibition of KB cells and human PLC/PRF/5 cells in vitro. 

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