Novel cytotoxic annonaceous acetogenins from Annona muricata.

@article{Chang2001NovelCA,
  title={Novel cytotoxic annonaceous acetogenins from Annona muricata.},
  author={Fang‐Rong Chang and Y. C. Wu},
  journal={Journal of natural products},
  year={2001},
  volume={64 7},
  pages={
          925-31
        }
}
  • F. Chang, Y. C. Wu
  • Published 7 July 2001
  • Biology, Chemistry
  • Journal of natural products
Seven new annonaceous acetogenins, muricins A-G (1-7), as well as five known compounds, a mixture of muricatetrocin A (8) and muricatetrocin B (9), longifolicin (10), corossolin (11), and corossolone (12), were isolated from the seeds of Annona muricata. The structures of all isolates were elucidated and characterized by spectral and chemical methods. These acetogenins showed significantly selective in vitro cytotoxicities toward the human hepatoma cell lines Hep G(2) and 2,2,15. 
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103 Citations
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