Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors.

Abstract

The aim of this study was to investigate the interaction of a series of novel compounds with leukotriene B(4) receptors (BLT) and vanilloid receptor (TRPV1). First, we characterized leukotriene B(4) (LTB(4)) ethanolamide. In guinea pig isolated lung parenchyma, LTB(4) ethanolamide antagonized the contractile action of LTB(4) with an apparent K(B) value of 7… (More)

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@article{Mchugh2006NovelCT, title={Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors.}, author={Douglas E. Mchugh and R. McMaster and Roger G Pertwee and Sucharita Roy and Anu Mahadevan and Raj K. Razdan and Ruth A. Ross}, journal={The Journal of pharmacology and experimental therapeutics}, year={2006}, volume={316 2}, pages={955-65} }