Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression.

Abstract

The successful clinical management of lung cancer is limited by frequent loss-of-function mutations in p53 which cooperates with chronic oxidant-stress induced adaptations in mercapturic acid pathway (MAP) which in turn regulates critical intracellular signaling cascades that determine therapeutic refractoriness. Hence, we investigated the anti-cancer… (More)
DOI: 10.1016/j.bcp.2013.09.022

6 Figures and Tables

Topics

  • Presentations referencing similar topics