Novel cofactor derivatives and cofactor-based models.

  title={Novel cofactor derivatives and cofactor-based models.},
  author={Pranab K. Mishra and Dale G. Drueckhammer},
  journal={Current opinion in chemical biology},
  volume={2 6},
In 1997 and the first half of 1998, numerous publications appeared reporting studies of cofactors and their analogues in classical model systems and in enzyme-catalyzed reactions directed at understanding the enzymatic reactions of their natural cofactors. Model systems based on flavins have provided new insights into enzymatic modulation of the flavin reduction potential, and enzymatic reactions of coenzyme A analogues and derivatives have been employed in several studies of coenzyme A… CONTINUE READING