Novel cluster of alpha-interferon gene sequences in a placental cosmid DNA library.

@article{Lund1984NovelCO,
  title={Novel cluster of alpha-interferon gene sequences in a placental cosmid DNA library.},
  author={Bjoern Lund and Thom Edlund and W. Lindenmaier and Theriault Ny and Jennifer Collins and Erik Lundgren and Alexander von Gabain},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 8},
  pages={
          2435-9
        }
}
A human cosmid library was constructed and probed with a human alpha interferon (IFN-alpha) cDNA clone. One clone giving a strong hybridizing signal was isolated and characterized. The cosmid DNA insert represents a section of the human genome containing three regions of IFN-alpha-like sequences. The DNA was characterized with restriction endonuclease mapping, thereby allowing comparison to similar linkage groups reported recently and determination of homologous regions on the known physical… CONTINUE READING