Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency

@article{Brock2016NovelCL,
  title={Novel ciliate lipases for enzyme replacement during exocrine pancreatic insufficiency},
  author={Alexander Brock and Ingo Aldag and Stella Edskes and Marcus WW Hartmann and Torsten Herzog and Waldemar Uhl and Juergen Schnekenburger},
  journal={European Journal of Gastroenterology \& Hepatology},
  year={2016},
  volume={28},
  pages={1305–1312}
}
Aim and objectives Exocrine pancreatic insufficiency caused by inflammation or pancreatic tumors results in nutrient malfunction by a lack of digestive enzymes and neutralization compounds. Despite satisfactory clinical results with current enzyme therapies, a normalization of fat absorption in patients is rare. An individualized therapy is required that includes high dosage of enzymatic units, usage of enteric coating, and addition of gastric proton pump inhibitors. The key goal to improve… 
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