Novel chicken CXC and CC chemokines.

  title={Novel chicken CXC and CC chemokines.},
  author={C Sick and Kirsten Schneider and Peter Staeheli and K C Weining},
  volume={12 3},
Upon stimulation with lipopolysaccharide (LPS) the chicken macrophage cell line HD-11 secretes factors with cytokine activity. To characterize these molecules, representational difference analysis with RNA of LPS-induced and uninduced HD-11 cells was performed. Two cDNA clones were isolated that code for polypeptides with structural features of chemokines. cDNA K60 codes for a novel CXC chemokine of 104 residues including a putative signal peptide of 20 amino acids at the N-terminus. It is 67… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…