Novel cataract mouse model using ddY strain: hereditary and histological characteristics.

@article{Kondo2010NovelCM,
  title={Novel cataract mouse model using ddY strain: hereditary and histological characteristics.},
  author={Tomohiro Kondo and Hiroaki Nagai and Hiroshi Morioka and Ken Takeshi Kusakabe and Toshiya Okada},
  journal={The Journal of veterinary medical science},
  year={2010},
  volume={72 2},
  pages={
          203-9
        }
}
A novel cataract model was identified in the ddY strain (outbred colony) reared at Osaka Prefecture University. Opacity appeared as a white pinpoint focus in the unpigmented eyes of cataract mice at 6 weeks of age. All mice, fully viable and fertile, were bilaterally affected by the time they were 10 weeks of age. There were no gender differences in the incidence of cataracts. Histologically, 5-month-old cataract mice showed vacuolation of epithelial cells, disruption of lens fibers, and… CONTINUE READING

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