Novel carbazole degradation genes of Sphingomonas CB3: sequence analysis, transcription, and molecular ecology.

@article{Shepherd1998NovelCD,
  title={Novel carbazole degradation genes of Sphingomonas CB3: sequence analysis, transcription, and molecular ecology.},
  author={John Michael Shepherd and Gareth Lloyd-Jones},
  journal={Biochemical and biophysical research communications},
  year={1998},
  volume={247 1},
  pages={129-35}
}
The degradation of aromatic compounds by bacteria is dependent upon specific catabolic operons. The unique car locus isolated from Sphingomonas CB3 encodes the first four enzymes involved in the catabolism of the azaarene carbazole. These include a class II three-component dioxygenase enzyme system, a dihydrodiol dehydrogenase, an extradiol (meta-cleavage) dioxygenase, and a hydrolase. Homology of deduced amino acid sequences is closer to corresponding biphenyl catabolic genes than to… CONTINUE READING
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