Novel candidate substrates of AMP-activated protein kinase identified in red blood cell lysates.

@article{Thali2010NovelCS,
  title={Novel candidate substrates of AMP-activated protein kinase identified in red blood cell lysates.},
  author={Ramon F. Thali and Roland D. Tuerk and Roland Scholz and Yolanda Yoho-Auchli and Ren{\'e} A. Brunisholz and Dietbert Neumann},
  journal={Biochemical and biophysical research communications},
  year={2010},
  volume={398 2},
  pages={296-301}
}
AMPK is a metabolic stress-sensing kinase with important functions for red blood cell (RBC) survival. By using a proteomic approach, we identified putative AMPK targets in hemoglobin-depleted lysates of RBC, including metabolic enzymes, cytoskeletal proteins and enzymes involved in the oxidative stress response. These data tie in with the phenotypic observations of AMPKalpha1-deficient RBC and provide reference for future studies.