Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach.


Comparative genomic hybridization (CGH) can reveal important disease genes but the large regions identified could sometimes contain hundreds of genes. Here we combine high-resolution CGH analysis of 598 human cancer cell lines with insertion sites isolated from 1,005 mouse tumors induced with the murine leukemia virus (MuLV). This cross-species oncogenomic… (More)
DOI: 10.1158/0008-5472.CAN-09-1737


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