Novel biochemical pathways of endoglin in vascular cell physiology.

@article{Bernabeu2007NovelBP,
  title={Novel biochemical pathways of endoglin in vascular cell physiology.},
  author={Carmelo Bernabeu and Barbara A. Conley and Calvin P. H. Vary},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={102 6},
  pages={
          1375-88
        }
}
The broad role of the transforming growth factor beta (TGFbeta) signaling pathway in vascular development, homeostasis, and repair is well appreciated. Endoglin is emerging as a novel, complex, and poorly understood regulatory component of the TGFbeta receptor complex, whose importance is underscored by its recognition as the site of mutations causing hereditary hemorrhagic telangiectasia (HHT) [McAllister et al., 1994]. Extensive analyses of endoglin function in normal developmental mouse… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 74 CITATIONS, ESTIMATED 55% COVERAGE

Endothelial cells of oral pyogenic granulomas express eNOS and CD105/endoglin: an immunohistochemical study.

VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Endoglin in human liver disease and murine models of liver fibrosis—A protective factor against liver fibrosis

FILTER CITATIONS BY YEAR

2008
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 114 REFERENCES

Hereditary haemorrhagic telangiectasia: mutation detection, test sensitivity and novel mutations.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Defective angiogenesis in mice lacking endoglin.

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

CD 105 and angiogenesis.

VIEW 4 EXCERPTS