Novel autoantibodies in Sjögren's syndrome: A comprehensive review.

  title={Novel autoantibodies in Sj{\"o}gren's syndrome: A comprehensive review.},
  author={Eduardo Mart{\'i}n-Nares and Gabriela Hern{\'a}ndez-Molina},
  journal={Autoimmunity reviews},
  volume={18 2},

Autoantibodies in Sjögren's syndrome and its classification criteria

Not all autoantibodies are clinically relevant. Classic and novel autoantibodies in Sjögren’s syndrome: A critical review

This paper critically review the classic and the novel autoantibodies in SjS, analyzing the methods employed for detection, the pathogenic role and the wide spectrum of clinical phenotypes.

Current State of Knowledge on Primary Sjögren’s Syndrome, an Autoimmune Exocrinopathy

The present comprehensive review of primary Sjögren’s syndrome addresses the clinical manifestations and complications of the disease, the diagnostic workup, the pathogenic mechanisms and the therapeutic approaches.

New frontiers in precision medicine for Sjogren’s syndrome

The perspectives of clinical and translational research are anticipated to define phenotypic clustering of high-risk Sjogren’s syndrome patients and link the clinical picture of the disease with fundamental molecular mechanisms and molecules implicated in pathogenesis.

Update on disease pathogenesis, diagnosis, and management of primary Sjögren’s syndrome

Many studies have tried to define pSS more accurately, to study its pathogenesis, to find effective treatment strategies, opening up new avenues for early diagnosis and precise management of pSS.

Management of Sjögren's Syndrome: Present Issues and Future Perspectives

The main issues that have been evoked to justify the poor results of the new therapeutic attempts are: the extreme variability of the disease phenotypes of the patients enrolled in the trials, which are dependent on different underlying patterns of biological mechanisms.

Why Should We Consider Potential Roles of Oral Bacteria in the Pathogenesis of Sjögren Syndrome?

Oral dysbiosis associated with SS and evidence for bacterial infection of the salivary glands in SS were reviewed and the added roles of bacteria may extend the understanding of the pathogenetic mechanisms and therapeutic approaches for this autoimmune exocrinopathy.

Serological Evidence for the Association Between Epstein-Barr Virus Infection and Sjögren’s Syndrome

Strong serological evidence is provided for the association between EBV infection and SjS with obvious associations with IgM-anti-VCA antibody and IgG- anti-EA antibody.

Characterisation of articular manifestations in primary Sjögren's syndrome: clinical and imaging features.

Imaging techniques such as US and MRI may be useful in the follow-up of pSS patients for prompt identification of AMs, for the quantification of their extent and ultimately for providing guidance on treatment and improving patient care.



Investigation of novel autoantibodies in Sjogren’s syndrome utilizing Sera from the Sjogren’s international collaborative clinical alliance cohort

Evaluating sera of well-characterized patients with dry eyes and dry mouth and lip biopsies from the Sjogren’s International Collaborative Clinical Alliance found anti-Ro and anti-La identify patients with SS and more severe disease than anti-SP1, anti-CA6, andAnti-PSP.

Novel autoantibodies in Sjogren's syndrome.

Investigation of three potential autoantibodies in Sjogren's syndrome and associated MALT lymphoma

Collectively, this study has successfully identified a panel of potential autoantigens that are progressively up-regulated during the development of pSS and its progression to MALT lymphoma.

Pathogenesis of Sjögren's syndrome.

Autoantibodies in Sjögren's Syndrome.

Identification of Moesin as a Novel Autoantigen in Patients with Sjögren's Syndrome.

An association between anti-moesin antibodies and SS manifestation have been found which may be considered a suspected serum biomarker for the development of SS.

Analysis of novel Sjogren’s syndrome autoantibodies in patients with dry eyes

Evaluated how many patients with idiopathic dry eye and no evidence of systemic diseases from a dry eye practice have these autoantibodies, which are included in the diagnostic criteria for SS, anti-Ro and anti-La.