Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

Abstract

UNLABELLED Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a major transcriptional regulator of lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates the expression of numerous genes in organs displaying high FA catabolic rates, including the liver. The role of this nuclear receptor as a sensor of… (More)

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Cite this paper

@article{Martin2007NovelAO, title={Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.}, author={Pascal G. P. Martin and Herv{\'e} Guillou and Fr{\'e}d{\'e}ric Lasserre and S{\'e}bastien D{\'e}jean and Annaig Lan and Jean Marc Pascussi and Magali Sancristobal and Philippe Legrand and Philippe Besse and Thierry Pineau}, journal={Hepatology}, year={2007}, volume={45 3}, pages={767-77} }